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Pharmaceuticals, Their Discovery, Regulation and Manufacture OLCC-3


Jim Beard,
Catawba College
Salisbury, NC 28144

Note: This article was scanned using OCR from the Spring 1998 CCCE Newsletter. Please contact us if you identify any OCR errors.
This is an invitation to register your school for the On-Line Chemistry Course for Upper Division Chemistry Students (Prerequisite - one year of organic chemistry) to be held during the Fall term of 1998. The on-line activities will be scheduled for September 14 to November 25, 1998. The title of the course will be "Pharmaceuticals, Their Discovery, Regulation and Manufacture." The course is sponsored by the American Chemical Society, Division of Chemical Education's Committee on Computers in Chemical Education (CCCE). In this course, the Internet will be used for discussions among students (student Listserv and WebBoard), faculty (faculty Listserv and Web Board) and experts, all from around the world.
1. Drug discovery including computer-aided design, combinatorial chemistry and other, earlier strategies
2. Development of clinically useable drugs including optimization of novel lead structures and assessment of pharmacodynamics, safety and efficacy of promising drug candidates
3. "Case studies" of the development and use of certain classes of widely used drugs including analgesics, antidepressants, anti-inflammatory drugs, antibiotics, AIDS and anti-cancer compounds
4. The FDA approval and FDA regulated testing process
1. To provide an opportunity for students to investigate frequently used processes for discovery and manufacture of pharmaceuticals used as drugs for man and other animals
2. To provide the opportunity for students to gain an understanding of the general procedures for drug testing, its limitations, analysis, use and regulation
3. To provide an electronic forum which permits students to interact with professionals who are involved with the processes in 1 and 2
4. To provide an environment in which students will interact locally and at a distance to do brain-storming, data-gathering, data analysis and problem-solving
5. To provide a forum for discovery of and discussion of industry's interaction with its regulatory, client and physical environment including such items as government inspections, user complaints and hazardous waste handling)
Students will participate in collaborative learning assignments where they can practice division of labor, teamwork, and individual responsibility. The Listservs and WebBoards will be used for the discussion of concepts and processes.
Instructors at local sites will guide "traditional" literature searches as well as on-line data-gathering. On-line, students will be guided by faculty and each other in their exploration of the content of this course. On-line questions from faculty will sometimes require critical thinking about industrial procedures in terms of a personal values framework.
It is the responsibility of each participating institution to register students and to provide college credit for the course. The role of the OLCC organizing committee and the CCCE is limited to assistance in organizing and administering electronic aspects of the course. The American Chemical Society will neither provide credit nor assess any fees. It is suggested that students receive three semester hours of credit for the course. It is the responsibility of each local faculty member to assign grades to their students. It is anticipated that a national evaluation will be administered.
For further information about previous on-line courses like this, see the Web Pages for OLCC-1 at cham-course/webpage.html and additional information and evaluations of OLCC-1 at http://www .clarkson .edu/ -rosen2/olcc.html.

Further information can also be obtained by contacting the course coordinator:

Dr. Lindy Harrison
Department of Chemistry
York College of Pennsylvania
York, PA 17405-7199
717-846-7788 X1210
Those interested in participating in this OLCC-3 course during the Fall of 1998 should complete a pre-registration form. Contact the OLCC-3 registration coordinator, Dr. James Beard, e-mail: to obtain the form.


03/30/98 to 04/02/98